Animated Alzheimer's Film Tangles Gets Star Screening Ahead of IFC Release

Tangles, an animated film about a family living with early-onset Alzheimer's disease, had a special screening in New York on Monday night, with Seth Rogen, Julia Louis-Dreyfus and Bryan Cranston taking part in a Q&A afterwards, according to Deadline. The event was held at the Regal Union Square cinema.

Early-onset Alzheimer's is a form of the disease that begins earlier in life, often before age 65. The film is based on a graphic memoir by Sarah Levitt, who also co-wrote the screenplay. Leah Nelson directs, produces and co-wrote the film, which began development in 2016.

The film is black-and-white and drawn in 2-D, meaning it uses flat, two-dimensional images rather than the three-dimensional computer models used in many recent animated features. Abbi Jacobson voices the lead role of Sarah. The wider voice cast includes Rogen, Cranston, Louis-Dreyfus and Beanie Feldstein.

Lauren Miller Rogen is among the producers, alongside Louis-Dreyfus, Point Grey, Monarch Media, Giant Ant and LYLAS Pictures. Monday's screening was presented by Hilarity for Charity, a non-profit founded by the Rogens to support families affected by Alzheimer's.

The film has a distribution plan already in place. IFC acquired Tangles earlier in 2026, and Sapan Studios teamed with IFC on the deal, according to Deadline. IFC will open the film for a qualifying run later in November 2026. A qualifying run is a short, paid theatrical booking in a set number of cities, which allows a film to become eligible for awards consideration. The wider release is set for early 2027.

For audiences, the key dates are simple. The film will reach cinemas in a limited run this month, and a broader release follows in the new year.